HIGHLIGHT
Xofluza

Xofluza

baloxavir marboxil

Manufacturer:

Roche

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Baloxavir marboxil
Indications/Uses
Acute uncomplicated influenza in patients ≥12 yr who have been symptomatic for no >48 hr.
Dosage/Direction for Use
Adult & adolescent ≥12 yr, at least 80 kg 80 mg as single dose, 40 kg to <80 kg 40 mg as single dose.
Administration
May be taken with or without food: Do not take w/ dairy products, Ca-fortified beverages, laxatives, antacids, or oral supplements containing Fe, Zn, Se, Ca or Mg.
Contraindications
Special Precautions
Hypersensitivity. Risk of bacterial infections. Avoid use w/ dairy products, Ca-fortified beverages, polyvalent cation-containing laxatives, antacids or oral supplements (eg, Ca, Fe, Mg, selenium or Zn). Pregnancy & lactation. Childn <12 yr. Elderly ≥65 yr.
Adverse Reactions
Diarrhea; bronchitis; nausea; nasopharyngitis; headache.
Drug Interactions
Decreased plasma conc w/ polyvalent cation-containing laxatives, antacids or oral supplements eg, Ca, Fe, Mg, selenium, Zn. Inhibited viral replication & decreased effectiveness of live attenuated influenza vaccine.
MIMS Class
ATC Classification
J05AX25 - baloxavir marboxil ; Belongs to the class of other antivirals. Used as a direct acting antiviral in the systemic treatment of viral infections.
Presentation/Packing
Form
Xofluza FC tab 20 mg
Packing/Price
4's
Form
Xofluza FC tab 40 mg
Packing/Price
1's
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